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African prehistory: A long-awaited landscape revealed through genomics

The first large-scale study of ancient human DNA from sub-Saharan Africa opens a long-awaited window into the identity of prehistoric populations in the region and how they moved around and replaced one another over the past 8000 years.

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• https://www.garvan.org.au/news-events/news/african-prehistory-a-long-awaited-landscape-revealed-through-genomics

Type 1 diabetes: Releasing the 'insulin handbrake' could make transplants a reality for thousands

A Garvan-led research team has shown that a new therapeutic approach can enhance insulin secretion by the pancreas, and has the potential to improve islet cell transplants in individuals with type 1 diabetes.

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• https://www.garvan.org.au/news-events/news/type-1-diabetes-releasing-the-insulin-handbrake

‘Partner in crime’ mutations work together to kickstart lymphoma and autoimmune disease

Australian researchers have uncovered ‘extraordinary cooperation’ between two DNA mutations that are often found together in lymphomas and leukaemias. The findings help us understand how immune cells can ‘go rogue’, behaving in ways that can lead to autoimmune diseases and to blood cancers.

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• https://www.garvan.org.au/news-events/news/2018partner-in-crime2019-mutations-work-together-to-kickstart-lymphoma-and-autoimmune-disease