First Class Facilities
The St Vincent’s Research Campus is the premier medical research hub in NSW which include the St Vincent’s Centre for Applied Medical Research, Garvan Institute for Medical Research, Victor Chang Cardiac Research Institute and The Kinghorn Cancer Centre. Supporting our research focus areas is outstanding research infrastructure, much of which is supported centrally via research platforms available to all research staff.
This is a state of the art facility for breeding and holding research mice for the research community. The facility houses the rapidly increasing number of genetically modified mice that are critical for progress in research across all health priority areas, including cancer, mental illness, arthritis, asthma, heart disease, diabetes and obesity.
The BioBank allows researchers and collaborators to store valuable samples in a centralised purpose built core essential facility which maximises sample integrity. Researchers from other institutions are attracted to store valuable samples at an off-site, well managed biorepository as a disaster recovery option. This Facility provides researchers with high quality biological tissues and samples that will translate to better health outcomes for patients.
Garvan scientists are developing methods and tools that help life scientists exploit these large datasets to gain insight into underlying biological and biomedical processes and use data visualization to communicate complex science to the general public via biomedical animations.
Garvan has built critical mass in bioinformatics expertise and computing infrastructure to enable analysis of large data sets arising from next generation sequencing and mass spectrometry, to build applications for management of clinical datasets and for biovisualisation.
The Kinghorn Centre for Clinical Genomics (KCCG) was established by the Garvan Institute in 2012 to advance the use of genomic information in patient care. Clinical genomics is a rapidly evolving field focused on the use of genomic sequencing information in patient diagnosis and treatment. KCCG employs world-leading DNA analysis technology and expertise in genetics, pathology and bioinformatics to deliver and interpret genome sequences for research and clinical use.
Established in 2009 with the purchase of three confocal microscopes, the VCCRI Confocal Microscope facility spans most user imaging needs. The facility is located on level 7 of the Lowy Packer Building and affords scientists ready access to high-end confocal microscopes. Imaging capabilities available include routine four channel imaging as well more advanced confocal techniques such as spectral imaging, electrophysiology, image tiling of large specimens and rapid live-cell imaging.
Microscopy is one of the Garvan Institute’s major capabilities. The Garvan has dedicated Microscopy functionality located throughout the Garvan and The Kinghorn Cancer Centre to provide researchers and visiting scientists with access to a state-of-the-art imaging techniques for single-molecules, organelles, cells, tissues, intra-vital and whole animal imaging.
The Garvan Molecular Genetics core facility (formerly the ACRF Facility for the Molecular Genetics of Cancer) offers high throughput services covering the areas of sequencing, mouse genotyping, SNP genotyping, methylation quantification and gene expression analysis. A diversity of platforms is available within the facility.
The PC3 laboratory at St Vincent's Centre for Applied Medical Research is a modern purpose built facility giving researchers the flexibility to handle a number of infective organisms and genetically modified organisms at any one time. This is the only PC3 facility with such capacity and enables unique research into the immunology, natural history and pathogenesis of these infections. Certification by OGTR ensures standards and work practices are complied with and permits research involving GMO to be carried out.
The Small Animal Physiology (SAP) work is undertaken in four separate facilities within the Lowy Packer Building. Staff are able to routinely determine cardiac morphology and functional capacity in the whole animal using echocardiography and at the organ and cellular levels using isolated heart Langendorff and calcium imaging of isolated myocytes, respectively.